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The differentiation and polarization of macrophages

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The differentiation and polarization of macrophages have been extensively studied, particularly with regard to transcriptional regulation. For instance, the PU.1 and C/EBP transcription factors are critical for the development of macrophages. M1 macrophage polarization by TLR ligands involves the activation … Continue reading

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trachomatis released from NK cell-exposed infected cells, pooled

trachomatis released from NK cell-exposed infected cells, pooled A2EN cell lysates and culture supernatants from C. trachomatis-infected cells cocultured with NK cells were compared with those cultured for the same period of time postinfection but in the absence of NK cells. … Continue reading

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, 2006; Lifshitz et al , 2009) The tissue-protective and immunom

, 2006; Lifshitz et al., 2009). The tissue-protective and immunomodulatory functions of Epo on the one hand and erythropoiesis on the other are mediated by different EpoR (Brines et al., 2004; Brines & Cerami, 2008). The hematopoietic receptor is a … Continue reading

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To identify new potential growth factors, we compared the express

To identify new potential growth factors, we compared the expression profile of IL-1β-stimulated ECs over 4, 8 and 16 h with non-stimulated ECs using oligonucleotide microarrays covering more than 46 000 transcripts. Most significant changes were detected after 4 h. Utilization of Gene … Continue reading

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One patient with adynamic bone disease subsequently developed bio

One patient with adynamic bone disease subsequently developed biochemical recurrence of hyperparathyroidism. Serial bone densitometry showed remarkable improvement. There was no fracture. Conclusion:  In the studied series of total parathyroidectomy without autoimplant, adynamic A-769662 research buy bone disease occurred in … Continue reading

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Here we report a rare case of IgG4RD that developed during chroni

Here we report a rare case of IgG4RD that developed during chronic hemodialysis. Case Report: A 61-year-old male with polycystic kidney disease who had been on hemodialysis for seven years was referred to our hospital because of nausea, cough and asthma … Continue reading

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For flow cytometry, the specific event acquisition gates were est

For flow cytometry, the specific event acquisition gates were established using appropriate isotype antibody controls. Freshly obtained PBMC (1 × 105–2 × 106) or enriched CD19+ cells from freshly obtained PBMC were stained with human-specific antibodies, purchased from BD Biosciences unless noted otherwise. Antibodies … Continue reading

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Following the cell cultures, the supernatants were collected for

Following the cell cultures, the supernatants were collected for measurements of IL-10 and TGF-β1 by enzyme immunoassay (EIA). Three-colour LY2109761 mouse flow cytometric analyses were performed at the optimal concentrations recommended by the manufacturer. Cells were stained with the appropriate … Continue reading

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Although level of pVL is closely associated with the rate of HIV

Although level of pVL is closely associated with the rate of HIV disease progression, it does not measure disease progression directly. We therefore calculated the rate of decline in CD4+ T cell counts (see the Materials and Methods), and investigated … Continue reading

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trachomatis-infected cells in vitro (Rasmussen et al , 1997) Sti

trachomatis-infected cells in vitro (Rasmussen et al., 1997). Still, the fact that increases in MICA are Adriamycin seen only on infected cells but not on uninfected bystanders in the same culture suggests that soluble mediators are not sufficient for these effects. … Continue reading

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