No patients suffered from ischemic event in perioperative period. Conclusion: Our data indicated that continued use of LDA did not increase the risk of bleeding after ER for CRNs. Key Word(s): 1. endoscopic resection; 2. colorectal neoplasm; 3. low dose aspirin; Presenting Author: TIAGOCÚRDIA GONÇALVES Additional Authors: JOANA
MAGALHÃES, PEDROBOAL CARVALHO, MARIAJOÃO MOREIRA, JOSÉ COTTER Corresponding Author: TIAGOCÚRDIA GONÇALVES Affiliations: Gastroenterology Opaganib Department – Centro Hospitalar do Alto Ave, Guimarães, Portugal Objective: Angioectasias are the most common vascular anomalies found in the gastrointestinal tract. When localized in the small bowel (SB) they can cause obscure gastrointestinal bleeding (OGIB) and in this setting, wireless
capsule endoscopy (WCE) is currently an important diagnostic tool. This study aimed to identify predictive factors for the presence of SB angioectasias, detected by WCE. Methods: We retrospectively analyzed the results of 284 WCE performed consecutively between April 2006 and December 2012, whose indication was OGIB. From these, 47 cases with SB angioectasias and 53 controls without identifiable lesions were chosen. For each selected patient demographic, clinical and laboratorial information on the exam date was collected. Statistical analysis was performed using SPSS v17.0. Results: The mean age of subjects with angioectasias http://www.selleckchem.com/products/Adrucil(Fluorouracil).html (70,9 ± 14,7) was significantly higher than in controls (53,1 ± 18,6; p < 0,05). Angioectasias were found in 56,1% of men and in 40,6% of women, although this difference did not reach statistical significance. The presence of angioectasias in SB was significantly higher when the indication for
the exam was overt OGIB (p < 0,05). 上海皓元 From past medical history, hypertension and dyslipidemia were the most significantly associated factors with the presence of SB angioectasias (p < 0,05), while smoking and chronic kidney disease were only marginally associated (p = 0,084; p = 0,145). Diabetes, aortic stenosis, chronic liver disease, previous abdominal surgery, and use of antiplatelet or anticoagulant drugs were not significantly associated with SB angioectasias. There was no relationship found with platelet count. Conclusion: In OGIB, factors such older age, overt OGIB, dyslipidemia or hypertension are predictive for the presence of SB angioectasias found by WCE. Key Word(s): 1. angioectasia; 2. capsule endoscopy; 3. obscure bleeding; Presenting Author: TIAGOCÚRDIA GONÇALVES Additional Authors: FRANCISCADIAS CASTRO, MARIAJOÃO MOREIRA, JOSÉ COTTER Corresponding Author: TIAGOCÚRDIA GONÇALVES Affiliations: Gastroenterology Department – Centro Hospitalar do Alto Ave Objective: Wireless capsule endoscopy (WCE) is currently a fundamental tool in the etiological study of obscure gastrointestinal bleeding (OGIB).