Those who smoked more than 10 cigarettes a day in 1991 had a 5 (95% CI: 1–8) percentage point lower probability of good health than those who have never smoked, and those who had no support in 1991 had a 16 (95% CI:
9–25) percentage point lower probability of good health. The coefficients for vegetable consumption and for friend/family relations are not statistically significant at conventional levels. The positive coefficient for drinking shrinks and loses statistical significance in model 1B, resulting from the age and gender adjustment: Those who drink more are younger and more often male, and the positive coefficient in model 1A was confounded by the better health of younger people and of men. Looking at health in 2010 (models 2A–2B), the risk differences are generally similar to those in models 1A–1B. However, the negative effect for heavy smokers as compared to non-smokers is larger at 10 percentage points Kinase Inhibitor Library (95% CI: 5–15, adjusted model), and the adjusted effects of social support and exercise are not statistically significant (model 2B). The coefficient for vegetable consumption is (barely) statistically significant, showing 4 percentage points [95% CI 0.2–7] higher probability of better health in 2010 for those who ate vegetables every day compared to those who did not. To make the results more intuitive, Fig. 1 gives the predicted probability
from model 1B DAPT concentration of bad health in 2000 for a type case, as described in the Methods section. A clustering of risk factors is related to a large risk of declining health: the “worst” combination of risk factors exemplified here (smoking 10 or more cigarettes a day, having no support and never exercise) gives a predicted probability of almost 50% of bad health for this type case, compared to only 15% for those who never smoke, exercise every week and have social support. The scope of this article is broad, analysing different life-style factors and general self-rated health over long time. 80% of the respondents with good health in 1991 have retained it in 2000/2010, while 20% report worse health.
We have studied how these 20% differ, in terms of their lifestyle in 1991, from those with persistently good health. The lifestyle Dipeptidyl peptidase effects on mortality are well established in the literature (citations above), and our results here suggest that health effects of smoking and exercise, and to some extent social support and vegetable consumption, are reflected also in the subjective sense of overall health. This may seem intuitive, but is not obvious as subjective health can incorporate factors not captured by mortality differences. The general pattern of results is also in line with the previous cross-sectional findings on self-rated health. For example, statistically significant associations in the same direction as here have been found on Swedish data for exercise (Manderbacka et al.