9-17.7 years) and from female psychiatric patients (n = 73), mean
age 16.8 years with a range of 14.5-18.4 years), with diagnoses of major depressive disorders (MDD) and anxiety disorders.\n\nResults: The SOC scores showed high inverse correlations to BDI, BAI and SDQ-em. In the non-clinical sample the correlation coefficient was -0.86 to -0.73 and in the clinical samples -0.74 to -0.53 (p < 0.001). Multiple Fedratinib regression models showed that BDI was the strongest predictor of SOC in the non-clinical (beta coefficient -0.47) and clinical sample (beta coefficient -0.52). The total degree of explanation of self assessed anxiety and depression on the SOC variance estimated by multiple R-2 = 0.74, adjusted R-2 = 0.73 in the non-clinical sample and multiple R-2 = 0.66, adjusted R-2 = 0.65 in the clinical sample. Multivariate analyses failed to isolate SOC as a separate construct and the SOC-scale, BDI, BAI and SDQ-em showed similar patterns of correlations to self-reported and physiological health parameters in both samples. The SOC-scale was the most stable measure over six months.\n\nConclusions: The SOC-scale did not appear to be a measure of a distinct salutogenic construct, but an inverse
measure of persistent depressive symptoms and generalized social anxiety similar to the diagnostic criteria for major depressive disorder (MDD), dysthymic disorder, generalized anxiety disorder (GAD) or generalized social anxiety disorder (SAD) according to DSM-IV. These symptoms were
better captured with SOC than by the specialized scales for anxiety and depression. Self-assessment selleck screening library scales that adequately identify MDD, dysthymic disorder, GAD and SAD need to be implemented. Comorbidity of these disorders is common in adolescent females and corresponds to a more severe symptomatology and impaired global function.”
“PETRASSI FA, HODKINSON PD, WALTERS PL, GAYDOS SJ. Hypoxic hypoxia at moderate altitudes: review of the state of the science. Aviat Space Environ Med 2012; 83:975-84.\n\nUnpressurized aircraft routinely operate at altitudes where hypoxia may be of concern. A systematic literature Selleckchem ABT737 review was conducted regarding hypoxic impairment, including mental functions, sensory deficits, and other pertinent research findings that may affect aviation-related duties at moderate altitude (8000 to 15,000 ft/2438 to 4572 m). The results of this review suggest that cognitive and psychomotor deficits may include learning, reaction time, decision-making, and certain types of memory. However, results are difficult to quantify and reliably reproduce. Inconsistency of results may be related to the subtlety of deficits compared to high altitude, differences among individual compensatory mechanisms, variation in methodology or sensitivity of metrics, presence or absence of exercise, heterogeneous neuronal central nervous system (CNS) response, and interindividual variation. Literature regarding hypoxic visual decrements is more consistent.