Sympathetic system seems

to be at least partially involve

Sympathetic system seems

to be at least partially involved in pathogenesis of distorted haemodynamics and stroke in OSA patients. However, there are still several open questions that need to be addressed before the effective therapeutic strategies can be implemented.”
“This study represents an original work aimed to recognize the main constitution of Trigonella berythea. The total phenolic content and total flavonoid content of leaves and stems of T berythea have been estimated. An extraction and purification of phenolic mixture compounds from the leaves and stems of this plant have been performed and their antioxidant potential using the DPPH, H2O2 and chelating of ferrous ions tests has BB-94 inhibitor been evaluated. Then, their cytotoxicity on the MCF7 breast cancer cell line by the XTT Cell Viability technique has been studied. Our results demonstrated that leaves of T. berythea had

higher total phenolic selleckchem content and total flavonoid content than stems. On the other hand, the six extract from leaves and stems of this plant demonstrated a high antioxidant potential reaches more than 80%. Also, extracts from leaves of T. berythea had the highest inhibitory effect on MCF7 and U937 cell growth than that of stems. This inhibition was more than 60% for all extracts. These results provide new insight into the health functions of leaves and stems and demonstrate that T berythea extracts can potentially have health benefits.”
“Background. Non-dipper pattern, characterized Geneticin by diminished nocturnal decline in blood pressure (BP), is associated with an increase in cardiovascular events. Carotid-femoral pulse wave

velocity (CF-PWV) has been accepted as the gold standard measurement of arterial stiffness. CF-PWV is a well-recognized predictor of an adverse cardiovascular outcome with higher predictive value than classical cardiovascular risk factors. In this study, we investigated the association between PWV as the surrogate of arterial stiffness and non-dipper pattern in untreated hypertensive patients. Methods. The present study was cross-sectional and observational. Hypertensive patients were diagnosed according to ambulatory BP measurements (mean BP >= 130/80 mmHg). Eighty-four hypertensive patients, consulted for initial evaluation of hypertension, were enrolled. CF-PWV as the indicator of arterial stiffness was measured by a validated tonometry system (SphygmoCor). Patients with the history of any cardiovascular disease were excluded from the study. Results. Fifty-six patients had non-dipper pattern and 28 patients had dipper pattern in the study.

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