TH-302 P450 Inhibitors was conducted at the Center for Family Planning

Ow, that the side effects, but also TH-302 P450 Inhibitors of the sexual implications, we wanted the quality Investigate t of life and sexual behavior in healthy women on oral contraceptive E2V/DNG. Materials and Methods This prospective L ngsschnittstudie Of open-label study was conducted at the Center for Family Planning Research Group for Sexology, Department of Radiological Sciences and mothers, faculty t of Medicine, University t of Catania, Italy. Conducted The study protocol was approved by the ethics committee of the department and in accordance with ethical guidelines of the Helsinki explanation Tion of 1975. A written Einverst Ndniserkl Tion was obtained from each woman before entering the study, and they received no money payment. The timing of the application was November 2009 to April 2010. Subjects and women who were OC research provide advice on Family Planning Research Group for Sexology invited to participate in the study. The sample consisted of 72 healthy white S studied women aged 18 to 48 years who were sexually active life with a partner for more than 6 months and were planning to take oral contraceptives for controlled Of the fertility of at least 1 year. The women were not even any type of hormonal contraception and showed no resistance-indications to the use of CO registration, k Rperliche and gyn Were ecological investigations and medical, surgical, and drug history were assessed, the W Hlbarkeit study hrleisten the criteria for inclusion and a-raf Pathway exclusion based on weight. We excluded women with PVD, the current vaginosis, vaginitis or dystrophic. In addition, women with a history of severe hypertension, thromboembolic disease, severe diabetes mellitus, obesity, Leberfunktionsst Changes, neoplasia hormonedependent, soup Onneux Pap result w excluded During the last 6 months prior to treatment, were pregnant within 6 months, smoking and / or drug abuse, or breastfeeding, use of psychotropic drugs, or with a partner, a sexual dysfunction. Inclusion criteria were menstrual cycle with ovulation. To the ovulation cycle best term, Ultrasound for 10 days, 13 and 16 of the cycle was performed, and serum concentrations of progesterone were treated with an enzyme immunoassay using commercially Measured ltlicher kits. The menstrual cycle was defined as ovulatory when the serum progesterone was 8 IU / ml and topics U Newspaper cards on which they recorded the intensity of t and duration of menstruation again. Instruments Each woman underwent a sexual history interview prior to the use of CO and followed the cycle of the third and sixth. To define female sexual dysfunction, were the definition and classification of the second report of the Consensus Conference for Development Policy DSE use. The Short Form 36 questionnaire validated to The quality of life Was used to evaluate t. The questionnaire contains 36 questions divided lt in eight categories: anxiety further functionability ability, Bosutinib anxiety further functionability ability, anxiety further pain, general health, vitality t, mental health, social functionability ability, and r is the operation emotionally. A visual analogue scale ranging from not at all to the 0 mm mark too much / very often was at the 100 mm mark also used. The women were instructed to place a marker at the point that best corresponded to their feelings. The SF-36 questionnaire at the beginning and 26 Given day of the Bo.